MedCA Medical Assistant Domain I Pharmacology Exam (Knowledge Base Review) Q & S

MedCA Medical Assistant

Domain I Pharmacology

Exam (Knowledge Base Review)

Q & S

2024

• A patient with chronic kidney disease requires a medication

adjustment. Which of the following medications should be used with caution due to potential nephrotoxicity?

• Metformin
• Lisinopril
• Ibuprofen
• Levothyroxine

Correct Answer: C. Ibuprofen

Rationale: Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID)

that can cause nephrotoxicity, especially in patients with preexisting kidney conditions.

• Which medication is contraindicated for use in patients with a known

history of angioedema?

• Furosemide
• Enalapril
• Atorvastatin
• Metoprolol

Correct Answer: B. Enalapril

Rationale: Enalapril, an ACE inhibitor, is contraindicated in patients with

a history of angioedema related to previous ACE inhibitor therapy due to the risk of recurrence.

• A 45-year-old male with hypertension and diabetes should be

cautioned about the concurrent use of which two medications due to the risk of hyperkalemia?

• Metformin and Glipizide
• Lisinopril and Spironolactone
• Aspirin and Clopidogrel
• Simvastatin and Ezetimibe

Correct Answer: B. Lisinopril and Spironolactone

Rationale: Both Lisinopril, an ACE inhibitor, and Spironolactone, a

potassium-sparing diuretic, can increase serum potassium levels, leading to hyperkalemia.

• When dispensing medications, which of the following is a crucial step

to ensure patient safety?

• Verifying patient identity
• Ensuring the medication is aesthetically pleasing
• Providing the cheapest medication available
• Dispensing the medication quickly

Correct Answer: A. Verifying patient identity

Rationale: Verifying patient identity is essential to prevent medication

errors and ensure that the right patient receives the correct medication and dosage.

• The brand name 'Tylenol' is associated with which generic medication?
• Ibuprofen
• Acetaminophen
• Naproxen
• Aspirin

Correct Answer: B. Acetaminophen

Rationale: Tylenol is the brand name for Acetaminophen, an analgesic

and antipyretic medication.

• Which of the following drug interactions could potentially increase the

risk of bleeding?

• Furosemide and Spironolactone
• Warfarin and Aspirin
• Metformin and Sitagliptin
• Amlodipine and Losartan

Correct Answer: B. Warfarin and Aspirin

Rationale: Both Warfarin, an anticoagulant, and Aspirin, an antiplatelet,

can increase the risk of bleeding when used together.

• A patient presents with an acute asthma attack. Which of the following

medications is indicated for immediate relief?

• Montelukast
• Fluticasone