NUR 2102 Pharmacology Unit 3 Study Guide

NUR 2102 Pharmacology Unit 3 Study Guide questions and answers solutions 2020/2021 Unit 3

Chapter 41:

What is the initial treatment for peptic ulcer disease?

Lifestyle changes: No smoking, no alcohol, reduce stress, don’t take NSAIDs

What are the medications for Peptic ulcer disease and GERD?Proton Pump Inhibitors H2 Antagonists Antacids Antibiotics

What does Carafate do?Carafate coats the ulcer, however you must take it frequently (4 times a day)

What does Reglan do?Reglan increases gastric emptying.

Proton Pump Inhibitor Prototype?Prilosec (omeprazole)

Nursing Implications for Prilosec?Do not crush or chew tablets.Long term use may increase risk of osteoporosis.

Prototype for H2 Receptor antagonists?Zantac (rinitadine)

Mechanism of action for H2 Receptor antagonist?

Blocks histamine from stimulating acid secreting parietal cells of the stomach.

Primary use of H2 Receptor antagonist?Heal duodenal and gastric ulcers Prevent stress ulcers in seriously ill hospitalized patients.

H2 Receptor Nursing Implications?Administer once a day after meals or at bed time Assess kidney or liver function Elevate Vitamin b12 in diet (animal flesh)

How do antacids work?Raises the pH of stomach acids to neutralize stomach acid.

What is the main adverse effect of antacids?Constipation.

Nursing Implications for antacids?Avoid milk Stools may appear white Administer 2 hours prior to other oral medications Contraindicated in patients with Kidney Stones

What is the treatment of H.Pylori?A combination of Flagyl, Biaxin (antibiotics), Omprazole (Proton Pump Inhibitor) and Pepto-Bismol (Bismuth)

Chapter 42

Laxatives used for...Colonoscopy? Stimulant Laxatives

Eye Surgery? Lubricant Laxatives To increase fecal mass? Bulk-forming agents

Treatment for mild diarrhea?Immodium (Loperamide), pepto bismol (bismuth), probiotics (Lacto bacillus)

Treatment for moderate to severe diarrhea?

Opioids: Lomotil (diphenoxylate with atropine)

What are contraindications for the use of antidiarrheals?Glaucoma and Liver Disease

Medication for treatment of gas?Mylicon (simethicone)

Which medications are given for vomiting?Compazine and Zofran (Zofran is the medication given to cancer patients)

Inflammatory bowel disease:

• Conditions associated with IBD? Chrons & Ulcerative Colitis

Symptoms? Abdominal cramping, frequent bowel movements, fever, weight loss, dehydration.

Treatment? Stair-step approach:

Step 1: Azulfidine (sulfasalazine), Dipentum (olsalazine), Asacol (mesalamine)

Step 2: Oral Corticosteriods

Step 3: Immunosuppresants —Immuran, Methotrexate, ifliximab (Remicade), TNF,

Humira (adalimumab), Entyvo (vedolizumab).

Contraindications for Azulfadine?Sulfa allergy